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EP 4 739 716 A1

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(43) Date of publication: 13.05.2026 Bulletin 2026/20 (21) Application number: 24838724.3 (22) Date of filing: 05.07.2024

(51) International Patent Classification (IPC):  C07K 16/46(2006.01) C07K 19/00(2006.01) A61P 35/00(2006.01) C07K 16/30(2006.01) A61K 39/395(2006.01) (52) Cooperative Patent Classification (CPC): A61P 35/00; C07K 16/2863; C07K 2317/31; C07K 2317/52; C07K 2317/77; C07K 2317/76; C07K 2317/73 (86) International application number: PCT/CN2024/103914 (87) International publication number: WO 2025/011471 (16.01.2025 Gazette 2025/03)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC ME MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA Designated Validation States: GE KH MA MD TN (30) Priority: 07.07.2023 CN 202310844573 03.11.2023 WO PCT/CN2023/129702 28.06.2024 CN 202410868126 (71) Applicant: Sichuan Kelun-Biotech Biopharmaceutical Co., Ltd. Chengdu, Sichuan 611138 (CN)

(72) Inventors: ZHENG, Yong Chengdu, Sichuan 611138 (CN) LEI, Dongmei Chengdu, Sichuan 611138 (CN) ZHOU, Yuehua Chengdu, Sichuan 611138 (CN) DI, Yanshu Chengdu, Sichuan 611138 (CN) YI, Shuting Chengdu, Sichuan 611138 (CN) LONG, Hu Chengdu, Sichuan 611138 (CN) LUO, Shuntao Chengdu, Sichuan 611138 (CN) YUAN, Xiaoxi Chengdu, Sichuan 611138 (CN) LI, Mingxiong Chengdu, Sichuan 611138 (CN) SHAN, Wei Chengdu, Sichuan 611138 (CN) LI, Senwu Chengdu, Sichuan 611138 (CN) SONG, Hongmei Chengdu, Sichuan 611138 (CN) TAN, Miao Chengdu, Sichuan 611138 (CN) TAN, Xiangyang Chengdu, Sichuan 611138 (CN) GE, Junyou Chengdu, Sichuan 611138 (CN) (74) Representative: Mathys & Squire  32 London Bridge Street The Shard London SE1 9SG London SE1 9SG (GB)