(19)
(11) EP 4 739 779 A2

(12)

(88) Date of publication A3:
03.04.2025

(43) Date of publication:
13.05.2026 Bulletin 2026/20

(21) Application number: 24836516.5

(22) Date of filing: 01.07.2024
(51) International Patent Classification (IPC): 
C12N 15/113(2010.01)
C12N 9/12(2006.01)
C12N 15/10(2006.01)
 A61K 38/46(2006.01)
C12N 9/22(2006.01)
C12N 15/86(2006.01)
(52) Cooperative Patent Classification (CPC):
C12N 2795/18122; C12N 9/1276; C12N 2310/20; C12N 15/102; C12N 15/907; C12N 9/22; C12N 9/127; C12Y 207/07049; C12Y 301/30001; C12N 15/113
(86) International application number:
PCT/US2024/036426
(87) International publication number:
WO 2025/010231 (09.01.2025 Gazette 2025/02)
(84) Designated Contracting States:
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC ME MK MT NL NO PL PT RO RS SE SI SK SM TR
Designated Extension States:
BA
Designated Validation States:
GE KH MA MD TN

(30) Priority: 03.07.2023 US 202363511710 P

(71) Applicant: Rutgers, the State University of New Jersey
New Brunswick, NJ 08901 (US)

(72) Inventor:
  • JIN, Shengkan
    Belle Mead, New Jersey 08502 (US)

(74) Representative: Hindles Limited 
Clarence House 131-135 George Street
Edinburgh, EH2 4JS
Edinburgh, EH2 4JS (GB)

   


(54) GENE EDITING MEDIATED BY REVERSE TRANSCRIPTION OF A MODULAR RNA TEMPLATE ANCHORED BY A TAG GRNA AND USES THEREOF