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EP 4 739 780 A1

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(43) Date of publication: 13.05.2026 Bulletin 2026/20 (21) Application number: 24739463.8 (22) Date of filing: 02.07.2024

(51) International Patent Classification (IPC):  C12N 15/62(2006.01) C07K 14/005(2006.01) C07K 16/10(2026.01) C07K 16/32(2006.01) C12N 15/10(2006.01) A61K 38/00(2006.01) C07K 16/00(2006.01) C07K 16/18(2006.01) C12N 7/00(2006.01) C12N 15/86(2006.01) (52) Cooperative Patent Classification (CPC): C07K 14/005; C12N 15/86; C12N 7/00; A61K 38/00; C12N 15/62; C07K 2317/565; C07K 2318/20; C07K 2317/92; C12N 2750/14122; C12N 2750/14143 (86) International application number: PCT/EP2024/068552 (87) International publication number: WO 2025/008323 (09.01.2025 Gazette 2025/02)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC ME MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA Designated Validation States: GE KH MA MD TN (30) Priority: 03.07.2023 US 202363511793 P (71) Applicant: UCB Biopharma SRL 1070 Brussels (BE)

(72) Inventors: KAS, Onur Yusuf 1070 Brussels (BE) KRAMER, Tal 1070 Brussels (BE) LAWSON, Alastair David Griffiths Slough Berkshire SL1 3WE (GB) MACPHERSON, Alexander Slough Berkshire SL1 3WE (GB) SCHULZE, Monika-Sarah Elisabeth Dorothea Slough Berkshire SL1 3WE (GB) XU, Meiyu 1070 Brussels (BE) (74) Representative: UCB Intellectual Property  c/o UCB IPD 208 Bath Road Slough, Berkshire SL1 3WE Slough, Berkshire SL1 3WE (GB)