(19)
(11) EP 4 739 781 A1

(12)

(43) Date of publication:
13.05.2026 Bulletin 2026/20

(21) Application number: 24740085.6

(22) Date of filing: 03.07.2024
(51) International Patent Classification (IPC): 
C12N 15/62(2006.01)
C12N 9/10(2006.01)
 C07K 14/47(2006.01)
C12N 9/22(2006.01)
(52) Cooperative Patent Classification (CPC):
C12N 9/22; C12N 9/1007; C12Y 201/01072; C07K 14/4702; C07K 2319/80; C07K 2319/70; C07K 2319/09; C12N 2310/20
(86) International application number:
PCT/EP2024/068764
(87) International publication number:
WO 2025/008414 (09.01.2025 Gazette 2025/02)
(84) Designated Contracting States:
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC ME MK MT NL NO PL PT RO RS SE SI SK SM TR
Designated Extension States:
BA
Designated Validation States:
GE KH MA MD TN

(30) Priority: 04.07.2023 EP 23183405

(71) Applicant: ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE (EPFL)
1015 Lausanne (CH)

(72) Inventors:
  • TRONO, Didier
    1134 Vufflens-le-Château (CH)
  • BEGNIS, Martina
    1197 Prangins (CH)

(74) Representative: KATZAROV S.A. 
Geneva Business Center 12 Avenue des Morgines
1213 Petit-Lancy
1213 Petit-Lancy (CH)

   


(54) SCAN-BASED FUSION PROTEINS FOR MODULATING GENE EXPRESSION AND METHODS OF USE