(19)

(11)

EP 4 739 782 A2

(12)

(88) Date of publication A3: 08.05.2025 (43) Date of publication: 13.05.2026 Bulletin 2026/20 (21) Application number: 24836561.1 (22) Date of filing: 03.07.2024

(51) International Patent Classification (IPC):  C12N 15/64(2006.01) G16B 35/00(2019.01) C12N 15/66(2006.01) (52) Cooperative Patent Classification (CPC): C12N 15/66 (86) International application number: PCT/US2024/036635 (87) International publication number: WO 2025/010306 (09.01.2025 Gazette 2025/02)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC ME MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA Designated Validation States: GE KH MA MD TN (30) Priority: 03.07.2023 US 202363511725 P (71) Applicant: Biosolutions Designs Frederick, MD 21704 (US)	(72) Inventors: REED, Thomas Boynton Beach, FL 33435 (US) SCHAUER, Stephen Rockkville, MD 20853 (US) PEPPEL, Austin Chesapeake, VA 23323 (US) (74) Representative: Gramm, Lins & Partner Patent- und Rechtsanwälte PartGmbB  Frankfurter Straße 3c 38122 Braunschweig 38122 Braunschweig (DE)