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(11)

EP 4 739 790 A1

(12)

(43) Date of publication: 13.05.2026 Bulletin 2026/20 (21) Application number: 24743574.6 (22) Date of filing: 25.06.2024

(51) International Patent Classification (IPC):  C12Q 1/6806(2018.01) (52) Cooperative Patent Classification (CPC): C12Q 1/6806   C-Sets: C12Q 1/6806, C12Q 2535/122, C12Q 2537/162, C12Q 2525/197, C12Q 2525/313, C12Q 2565/537; (86) International application number: PCT/US2024/035395 (87) International publication number: WO 2025/010160 (09.01.2025 Gazette 2025/02)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC ME MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA Designated Validation States: GE KH MA MD TN (30) Priority: 06.07.2023 US 202363525275 P (71) Applicant: Pacific Biosciences of California, Inc. Menlo Park, CA 94025 (US)	(72) Inventors: PATTERSON, Kurt Menlo Park, California 94025 (US) SHEN, Min-Jui Richard Menlo Park, California 94025 (US) ROHRMAN, Brittany Ann Menlo Park, California 94025 (US) SPARKS, Andrew Menlo Park, California 94025 (US) HUROWITZ, Evan Menlo Park, California 94025 (US) (74) Representative: Williams, Andrea  Marks & Clerk LLP 62-68 Hills Road Cambridge CB2 1LA Cambridge CB2 1LA (GB)