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(11)

EP 4 770 618 A1

(12)

(43) Date of publication: 08.07.2026 Bulletin 2026/28 (21) Application number: 24764831.4 (22) Date of filing: 30.08.2024

(51) International Patent Classification (IPC):  A61K 9/06(2006.01) A61K 47/02(2006.01) A61K 47/32(2006.01) A61K 9/00(2006.01) A61K 9/20(2006.01) A61K 47/10(2017.01) A61K 47/36(2006.01) (52) Cooperative Patent Classification (CPC): A61K 9/205; A61K 9/2031; A61K 9/2027; A61K 9/06; A61K 9/2009; A61K 9/2095; A61K 47/36; A61K 47/32; A61K 47/10; A61K 47/02; A61K 9/0056; A61K 9/006 (86) International application number: PCT/EP2024/074239 (87) International publication number: WO 2025/046044 (06.03.2025 Gazette 2025/10)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC ME MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA Designated Validation States: GE KH MA MD TN (30) Priority: 01.09.2023 EP 23194881 (71) Applicant: F. Hoffmann-La Roche AG 4070 Basel (CH)	(72) Inventors: KÜHL, Peter 4070 Basel (CH) LAI, Si Ying 4070 Basel (CH) WAGNER-HATTLER, Leonie Flurina Claude 4070 Basel (CH) (74) Representative: Beyermann, Jochen Carl  F. Hoffmann-La Roche AG CLP - Patent Department Grenzacherstrasse 124 4070 Basel 4070 Basel (CH)