(19)
(11) EP 4 770 642 A2

(12)

(88) Date of publication A3:
17.04.2025

(43) Date of publication:
08.07.2026 Bulletin 2026/28

(21) Application number: 24861080.0

(22) Date of filing: 29.08.2024
(51) International Patent Classification (IPC): 
A61K 31/425(2006.01)
C07D 257/04(2006.01)
A61P 35/00(2006.01)
(52) Cooperative Patent Classification (CPC):
A61P 35/00; A61K 45/06; A61K 31/519; A61K 31/506; A61K 31/425; A61K 31/55; A61K 2039/505; A61K 39/395; C07K 16/2863; C07K 2317/76; C07K 2317/24
 
C-Sets:
  1. A61K 39/395, A61K 2300/00;
  2. A61K 31/519, A61K 2300/00;
  3. A61K 31/506, A61K 2300/00;
  4. A61K 31/425, A61K 2300/00;
  5. A61K 31/55, A61K 2300/00;

(86) International application number:
PCT/US2024/044534
(87) International publication number:
WO 2025/049814 (06.03.2025 Gazette 2025/10)
(84) Designated Contracting States:
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC ME MK MT NL NO PL PT RO RS SE SI SK SM TR
Designated Extension States:
BA
Designated Validation States:
GE KH MA MD TN

(30) Priority: 01.09.2023 US 202363580096 P
11.10.2023 US 202363589547 P

(71) Applicant: Boundless Bio, Inc.
San Diego, CA 92121 (US)

(72) Inventors:
  • HANSEN, Ryan
    San Diego, California 92121 (US)
  • CHOWDHRY, Sudhir
    San Diego, California 92121 (US)
  • KASIBHATLA, Shailaja
    San Diego, California 92121 (US)
  • WAGNER, Klaus Wolfgang
    San Diego, California 92121 (US)
  • HASSIG, Christian
    San Diego, California 92121 (US)

(74) Representative: Mewburn Ellis LLP 
Aurora Building Counterslip
Bristol BS1 6BX
Bristol BS1 6BX (GB)

   


(54) RIBONUCLEOTIDE REDUCTASE (RNR) COMPOSITIONS AND METHODS OF USE