(19)
(11) EP 4 770 654 A1

(12)

(43) Date of publication:
08.07.2026 Bulletin 2026/28

(21) Application number: 24773176.3

(22) Date of filing: 28.08.2024
(51) International Patent Classification (IPC): 
A61K 35/28(2015.01)
A61P 37/06(2006.01)
(52) Cooperative Patent Classification (CPC):
A61K 35/28; A61P 37/06
(86) International application number:
PCT/IB2024/058375
(87) International publication number:
WO 2025/046491 (06.03.2025 Gazette 2025/10)
(84) Designated Contracting States:
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC ME MK MT NL NO PL PT RO RS SE SI SK SM TR
Designated Extension States:
BA
Designated Validation States:
GE KH MA MD TN

(30) Priority: 28.08.2023 US 202363579213 P

(71) Applicant: Mesoblast International Sàrl
1217 Meyrin (CH)

(72) Inventors:
  • ITESCU, Silviu
    Melbourne, Victoria 3000 (AU)
  • HAYES, Jack
    New York, New York 10017 (US)

(74) Representative: HGF 
HGF Limited 4th Floor, 1 City Square
Leeds LS1 2ES
Leeds LS1 2ES (GB)

   


(54) THIRD LINE TREATMENT FOR GVHD