(19)
(11) EP 4 770 655 A1

(12)

(43) Date of publication:
08.07.2026 Bulletin 2026/28

(21) Application number: 24861127.9

(22) Date of filing: 30.08.2024
(51) International Patent Classification (IPC): 
A61K 35/28(2015.01)
C12N 5/0775(2010.01)
 A61K 45/06(2006.01)
(52) Cooperative Patent Classification (CPC):
A61K 45/06; C12N 5/0607; C12N 2513/00; C12N 5/0605; C12N 2502/025; A61K 31/352; A61K 31/4375; A61K 31/12; A61K 31/05; A61K 38/1709; A61K 35/545
 
C-Sets:
  1. A61K 38/1709, A61K 2300/00;
  2. A61K 35/545, A61K 2300/00;
  3. A61K 31/352, A61K 2300/00;
  4. A61K 31/4375, A61K 2300/00;
  5. A61K 31/12, A61K 2300/00;
  6. A61K 31/05, A61K 2300/00;
(86) International application number:
PCT/US2024/044637
(87) International publication number:
WO 2025/049883 (06.03.2025 Gazette 2025/10)
(84) Designated Contracting States:
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC ME MK MT NL NO PL PT RO RS SE SI SK SM TR
Designated Extension States:
BA
Designated Validation States:
GE KH MA MD TN

(30) Priority: 30.08.2023 US 202363535407 P

(71) Applicant: JLM ExoGrade, LLC
Austin, TX 78746 (US)

(72) Inventors:
  • COLGAN, Michael
    Austin, TX 78746 (US)
  • DARINSKAS, Adas
    44281 Kaunas (LT)

(74) Representative: Maiwald GmbH 
Elisenhof Elisenstraße 3
80335 München
80335 München (DE)

   


(54) COMPOSITIONS AND METHODS FOR TREATING A DISEASE OR DISORDER ASSOCIATED WITH SENESCENCE