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(11)

EP 4 770 657 A1

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(43) Date of publication: 08.07.2026 Bulletin 2026/28 (21) Application number: 24769435.9 (22) Date of filing: 30.08.2024

(51) International Patent Classification (IPC):  A61K 38/00(2006.01) A61K 47/54(2017.01) C07K 7/08(2006.01) (52) Cooperative Patent Classification (CPC): C07K 7/08; A61K 47/551; A61K 47/60 (86) International application number: PCT/GB2024/052271 (87) International publication number: WO 2025/046244 (06.03.2025 Gazette 2025/10)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC ME MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA Designated Validation States: GE KH MA MD TN (30) Priority: 01.09.2023 US 202363579985 P 02.11.2023 US 202363595399 P (71) Applicant: BicycleTx Limited Cambridge CB21 6GS (GB)

(72) Inventors: DODS, Rachel Cambridge Cambridgeshire CB21 6GS (GB) CHEN, Liuhong Cambridge Cambridgeshire CB21 6GS (GB) MUDD, Gemma Cambridge Cambridgeshire CB21 6GS (GB) MCDONNELL, Kevin Cambridge Cambridgeshire CB21 6GS (GB) LU, Haw Cambridge Cambridgeshire CB21 6GS (GB) HILL, Katie Cambridge Cambridgeshire CB21 6GS (GB) HAMMER, Robert Cambridge Cambridgeshire CB21 6GS (GB) GOODFIELD, Laura Cambridge Cambridgeshire CB21 6GS (GB) UHLENBROICH, Sandra Cambridge Cambridgeshire CB21 6GS (GB) (74) Representative: J A Kemp LLP  80 Turnmill Street London EC1M 5QU London EC1M 5QU (GB)