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EP 4 770 672 A1

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(43) Date of publication: 08.07.2026 Bulletin 2026/28 (21) Application number: 24773261.3 (22) Date of filing: 30.08.2024

(51) International Patent Classification (IPC):  A61K 40/00(2025.01) A61K 39/00(2006.01) C07K 16/28(2006.01) A61P 35/02(2006.01) (52) Cooperative Patent Classification (CPC): C07K 16/2887; C07K 16/2803; C07K 2317/622; C07K 2317/73; A61P 35/02; A61K 40/4212; A61K 40/4221; A61K 40/4211; A61K 40/31; A61K 40/11 (86) International application number: PCT/US2024/044761 (87) International publication number: WO 2025/049972 (06.03.2025 Gazette 2025/10)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC ME MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA Designated Validation States: GE KH MA MD TN (30) Priority: 01.09.2023 US 202363536301 P 05.12.2023 US 202363606343 P (71) Applicant: CARGO Therapeutics, Inc. San Carlos, California 94070 (US)

(72) Inventors: BYERS, James San Carlos, California 94070 (US) BETHUNE, Michael San Carlos, California 94070 (US) SIEGEL, Matthew San Carlos, California 94070 (US) WANG, Lingyan San Carlos, California 94070 (US) KOO-MCCOY, Samantha San Carlos, California 94070 (US) LIAO, Eric San Carlos, California 94070 (US) QUACH, Boi San Carlos, California 94070 (US) BENTLEY, Trevor San Carlos, California 94070 (US) YI, Michael San Carlos, California 94070 (US) SAGIV-BARFI, Idit San Carlos, California 94070 (US) NGUYEN, Nhung San Carlos, California 94070 (US) (74) Representative: J A Kemp LLP  80 Turnmill Street London EC1M 5QU London EC1M 5QU (GB)