(19)
(11) EP 4 770 674 A2

(12)

(88) Date of publication A3:
22.05.2025

(43) Date of publication:
08.07.2026 Bulletin 2026/28

(21) Application number: 24861174.1

(22) Date of filing: 30.08.2024
(51) International Patent Classification (IPC): 
A61K 45/06(2006.01)
(52) Cooperative Patent Classification (CPC):
A61K 45/06
(86) International application number:
PCT/US2024/044753
(87) International publication number:
WO 2025/049966 (06.03.2025 Gazette 2025/10)
(84) Designated Contracting States:
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC ME MK MT NL NO PL PT RO RS SE SI SK SM TR
Designated Extension States:
BA
Designated Validation States:
GE KH MA MD TN

(30) Priority: 01.09.2023 US 202363580112 P

(71) Applicant: Institute For Cancer Research d/b/a The Research Institute of Fox Chase Cancer Center
Philadelphia, PA 19111-2497 (US)

(72) Inventor:
  • WASIK, Mariusz, A.
    Philadelphia, PA 19111-2497 (US)

(74) Representative: CH Kilger Anwaltspartnerschaft mbB 
Fasanenstraße 29
10719 Berlin
10719 Berlin (DE)

   


(54) METHODS AND COMPOSITIONS FOR INCREASING ROR1 EXPRESSION