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(11)

EP 4 770 676 A1

(12)

(43) Date of publication: 08.07.2026 Bulletin 2026/28 (21) Application number: 24860969.5 (22) Date of filing: 28.08.2024

(51) International Patent Classification (IPC):  A61K 47/54(2017.01) A61K 31/713(2006.01) A61P 1/16(2006.01) A61P 37/00(2006.01) A61K 31/7105(2006.01) A61K 47/61(2017.01) A61P 35/00(2006.01) C12N 15/113(2010.01) (52) Cooperative Patent Classification (CPC): A61K 47/549; C12N 15/113; C12N 2310/14; C12N 15/111; C12N 2320/32; A61K 31/7105; A61K 31/713 (86) International application number: PCT/US2024/044273 (87) International publication number: WO 2025/049634 (06.03.2025 Gazette 2025/10)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC ME MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA Designated Validation States: GE KH MA MD TN (30) Priority: 29.08.2023 US 202363579419 P (71) Applicant: Ganna Merger Sub, Inc. Watertown, MA 02472 (US)	(72) Inventors: BISARIA, Namita Watertown, MA 02472 (US) WEI, Mohui Watertown, MA 02472 (US) (74) Representative: Mathys & Squire  32 London Bridge Street The Shard London SE1 9SG London SE1 9SG (GB)