A CRYSTALLINE FORM OF 2-(3-(2,,5'-DIFLUORO-[1,1'-BIPHENYL]-4-YL)-2-OXOTETRAHYDROPYRIMIDIN-1(2H)-YL)-4-METHYLTHIAZOLE-5-SULFONAMIDE - Patent 4770752

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EP 4 770 752 A1

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(43)	Date of publication:
	08.07.2026 Bulletin 2026/28

(21)	Application number: 24773576.4

(22)	Date of filing: 27.08.2024

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International Patent Classification (IPC):

A61P 31/20^(2006.01)
C07D 417/04^(2006.01)

A61K 31/496^(2006.01)

(52)	Cooperative Patent Classification (CPC):
	C07D 417/04; A61P 31/20; A61K 31/513; A61K 45/06; A61P 31/22

(86)	International application number:
	PCT/IB2024/058309

(87)	International publication number:
	WO 2025/046456 (06.03.2025 Gazette 2025/10)

(84)	Designated Contracting States:
	AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC ME MK MT NL NO PL PT RO RS SE SI SK SM TR
	Designated Extension States:
	BA
	Designated Validation States:
	GE KH MA MD TN

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Priority:

28.08.2023 US 202363579070 P

(71)	Applicant: Assembly Biosciences, Inc.
	South San Francisco, CA 94080 (US)

(72)	Inventors:
	ZONG, Zhixin San Francisco, California 94080 (US) WU, Yi San Francisco, California 94080 (US)

(74)	Representative: Carpmaels & Ransford LLP
	One Southampton Row London WC1B 5HA London WC1B 5HA (GB)

(54)	A CRYSTALLINE FORM OF 2-(3-(2,,5'-DIFLUORO-[1,1'-BIPHENYL]-4-YL)-2-OXOTETRAHYDROPYRIMIDIN-1(2H)-YL)-4-METHYLTHIAZOLE-5-SULFONAMIDE