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(11)

EP 4 771 031 A1

(12)

(43) Date of publication: 08.07.2026 Bulletin 2026/28 (21) Application number: 24773227.4 (22) Date of filing: 29.08.2024

(51) International Patent Classification (IPC):  C07K 7/06(2006.01) A61P 25/00(2006.01) C07K 5/083(2006.01) A61K 38/00(2006.01) (52) Cooperative Patent Classification (CPC): C07K 7/06; C07K 5/0808; A61P 25/00; A61K 47/60 (86) International application number: PCT/US2024/044319 (87) International publication number: WO 2025/049670 (06.03.2025 Gazette 2025/10)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC ME MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA Designated Validation States: GE KH MA MD TN (30) Priority: 31.08.2023 US 202363536009 P (71) Applicant: Northwestern University Evanston, IL 60208 (US)	(72) Inventors: BURGDORF, Jeffrey S. Evanston, Illinois 60208 (US) MOSKAL, Joseph R. Evanston, Illinois 60208 (US) (74) Representative: Hoffmann Eitle  Patent- und Rechtsanwälte PartmbB Arabellastraße 30 81925 München 81925 München (DE)