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EP 4 771 032 A1

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(43) Date of publication: 08.07.2026 Bulletin 2026/28 (21) Application number: 24762678.1 (22) Date of filing: 30.08.2024

(51) International Patent Classification (IPC):  C07K 7/08(2006.01) A61P 25/00(2006.01) G01N 33/68(2006.01) A61K 38/00(2006.01) (52) Cooperative Patent Classification (CPC): G01N 33/6896; C07K 7/08; A61P 25/00; G01N 2800/2821 (86) International application number: PCT/EP2024/074244 (87) International publication number: WO 2025/046049 (06.03.2025 Gazette 2025/10)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC ME MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA Designated Validation States: GE KH MA MD TN (30) Priority: 31.08.2023 EP 23194706 18.04.2024 EP 24171065 (71) Applicant: Universiteit Utrecht Holding B.V. 3584 CS Utrecht (NL)	(72) Inventors: RÜDIGER, Stefan Georg Diethard 3584 CS Utrecht (NL) ARAGONÈS PEDROLA, Júlia 3584 CS Utrecht (NL) DEKKER, Françoise Aline 3584 CS Utrecht (NL) FRIEDLER, Assaf 3584 CS Utrecht (NL) MAYER, Guy 3584 CS Utrecht (NL) GARFAGNINI, Tommaso 3584 CS Utrecht (NL) (74) Representative: Nederlandsch Octrooibureau  P.O. Box 29720 2502 LS The Hague 2502 LS The Hague (NL)