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(11)

EP 4 771 034 A1

(12)

(43) Date of publication: 08.07.2026 Bulletin 2026/28 (21) Application number: 24764841.3 (22) Date of filing: 30.08.2024

(51) International Patent Classification (IPC):  C07K 14/00(2006.01) C07K 14/32(2006.01) C12R 1/07(2006.01) B82Y 5/00(2011.01) C12N 1/20(2026.01) (52) Cooperative Patent Classification (CPC): C07K 14/32; C07K 14/001; C12N 1/20; C12R 2001/07; C12R 2001/075 (86) International application number: PCT/EP2024/074370 (87) International publication number: WO 2025/046122 (06.03.2025 Gazette 2025/10)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC ME MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA Designated Validation States: GE KH MA MD TN (30) Priority: 01.09.2023 EP 23194950 (71) Applicants: VIB VZW 9052 Gent (BE) Vrije Universiteit Brussel 1050 Brussel (BE)	(72) Inventors: REMAUT, Ham 1050 Brussel (BE) SLEUTEL, Mike 1050 Brussel (BE) SOGUES CASTREJON, Adria 1050 Brussel (BE) COOMAN, Vita 1050 Brussel (BE)