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(11)

EP 4 771 036 A1

(12)

(43) Date of publication: 08.07.2026 Bulletin 2026/28 (21) Application number: 24765381.9 (22) Date of filing: 30.08.2024

(51) International Patent Classification (IPC):  C07K 14/21(2006.01) C12N 9/10(2006.01) C12P 19/14(2006.01) C12N 1/20(2026.01) C12N 9/42(2006.01) C12R 1/39(2006.01) (52) Cooperative Patent Classification (CPC): C12N 1/20; C12N 9/1059; C12N 9/2437; C12R 2001/39; C12Y 204/01012; C12Y 302/01004; C07K 14/21; C12P 19/04; C12N 15/52 (86) International application number: PCT/EP2024/074298 (87) International publication number: WO 2025/046078 (06.03.2025 Gazette 2025/10)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC ME MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA Designated Validation States: GE KH MA MD TN (30) Priority: 01.09.2023 GB 202313342 (71) Applicant: CroBio Ltd Macclesfield, Cheshire SK10 4TG (GB)	(72) Inventor: MULHALL, Ross Macclesfield Cheshire SK10 4TG (GB) (74) Representative: Mewburn Ellis LLP  Aurora Building Counterslip Bristol BS1 6BX Bristol BS1 6BX (GB)