(19)
(11) EP 4 771 037 A1

(12)

(43) Date of publication:
08.07.2026 Bulletin 2026/28

(21) Application number: 24789939.6

(22) Date of filing: 02.10.2024
(51) International Patent Classification (IPC): 
C07K 14/315(2006.01)
C07K 7/00(2006.01)
(52) Cooperative Patent Classification (CPC):
C07K 14/315; C07K 7/08; C07K 17/00
(86) International application number:
PCT/GB2024/052526
(87) International publication number:
WO 2025/074091 (10.04.2025 Gazette 2025/15)
(84) Designated Contracting States:
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC ME MK MT NL NO PL PT RO RS SE SI SK SM TR
Designated Extension States:
BA
Designated Validation States:
GE KH MA MD TN

(30) Priority: 02.10.2023 GB 202315107

(71) Applicants:
  • Oxford University Innovation Limited
    Oxford, Oxfordshire OX2 0JB (GB)
  • KING'S COLLEGE LONDON
    London, Greater London WC2R 2LS (GB)

(72) Inventors:
  • READING, Eamonn
    London Greater London WC2R 2LS (GB)
  • HAMMERSCHMID, Dietmar
    London Greater London WC2R 2LS (GB)
  • HOWARTH, Mark
    Oxford Oxfordshire OX1 3QU (GB)
  • KEEBLE, Anthony
    Oxford Oxfordshire OX1 3QU (GB)

(74) Representative: Dehns 
10 Old Bailey
London EC4M 7NG
London EC4M 7NG (GB)

   


(54) POLYPEPTIDES AND PEPTIDE TAGS CAPABLE OF SPONTANEOUS ISOPEPTIDE BOND FORMATION AT LOW TEMPERATURE AND LOW PH AND USES THEREOF