(19)

(11)

EP 4 771 038 A2

(12)

(88) Date of publication A3: 17.04.2025 (43) Date of publication: 08.07.2026 Bulletin 2026/28 (21) Application number: 24769548.9 (22) Date of filing: 28.08.2024

(51) International Patent Classification (IPC):  C07K 14/395(2006.01) C12N 1/18(2026.01) C12N 9/04(2006.01) C12N 9/16(2006.01) C12C 12/04(2006.01) C12C 12/00(2006.01) C12N 9/00(2006.01) C12N 9/10(2006.01) C12N 9/88(2006.01) (52) Cooperative Patent Classification (CPC): C12N 9/1029; C12N 9/88; C12N 9/0006; C12N 9/1085; C12N 9/16; C12N 1/18; C12N 9/00; C12Y 203/01084; C12Y 404/00; C12Y 101/01034; C12Y 205/0101; C12Y 402/03025; C12Y 301/07011; C12C 12/006; C12C 12/004; C12C 12/04; C07K 14/395; Y02E 50/10 (86) International application number: PCT/US2024/044299 (87) International publication number: WO 2025/049654 (06.03.2025 Gazette 2025/10)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC ME MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA Designated Validation States: GE KH MA MD TN (30) Priority: 28.08.2023 US 202363579269 P (71) Applicant: Berkeley Fermentation Science Inc. San Leandro, CA 94578 (US)	(72) Inventors: ROOP, Jeremy San Leandro, California 94578 (US) LIU, Daniel San Leandro, California 94578 (US) HARRIS, Nicholas San Leandro, California 94578 (US) DENBY, Charles San Leandro, California 94578 (US) SMITH, Thomas San Leandro, California 94578 (US) (74) Representative: Hoffmann Eitle  Patent- und Rechtsanwälte PartmbB Arabellastraße 30 81925 München 81925 München (DE)