(19)
(11) EP 4 771 053 A1

(12)

(43) Date of publication:
08.07.2026 Bulletin 2026/28

(21) Application number: 24858554.9

(22) Date of filing: 27.08.2024
(51) International Patent Classification (IPC): 
C07K 16/28(2006.01)
A61K 39/395(2006.01)
 C07K 14/725(2006.01)
A61P 35/00(2006.01)
(52) Cooperative Patent Classification (CPC):
A61P 35/00; C07K 16/2809; C07K 2317/22; C07K 2317/569; C07K 2317/92; C07K 2317/75; C07K 2317/31; C07K 16/2803; C07K 2317/73; C07K 2317/24
(86) International application number:
PCT/CN2024/114730
(87) International publication number:
WO 2025/045018 (06.03.2025 Gazette 2025/10)
(84) Designated Contracting States:
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC ME MK MT NL NO PL PT RO RS SE SI SK SM TR
Designated Extension States:
BA
Designated Validation States:
GE KH MA MD TN

(30) Priority: 31.08.2023 WO PCT/CN2023/116291
11.10.2023 WO PCT/CN2023/123953

(71) Applicants:
  • Legend Biotech Ireland Limited
    Dublin 18, D18 T934 (IE)
  • Legend Biotech USA Inc.
    Somerset, NJ 08873 (US)

(72) Inventors:
  • YANG, Shuai
    Nanjing, Jiangsu 211100 (CN)
  • TU, Xiaojie
    Nanjing, Jiangsu 211100 (CN)
  • WANG, Sujuan
    Nanjing, Jiangsu 211100 (CN)
  • ZHONG, Shengwei
    Nanjing, Jiangsu 211100 (CN)
  • SHU, Chenyu
    Nanjing, Jiangsu 211100 (CN)
  • ZENG, Wenwen
    Nanjing, Jiangsu 211100 (CN)
  • LI, Xiu
    Nanjing, Jiangsu 211100 (CN)
  • GAO, Qi
    Nanjing, Jiangsu 211100 (CN)
  • ZHANG, Yafeng
    Nanjing, Jiangsu 211100 (CN)
  • WU, Shu
    Nanjing, Jiangsu 211100 (CN)

(74) Representative: Murgitroyd & Company 
165-169 Scotland Street
Glasgow G5 8PL
Glasgow G5 8PL (GB)

   


(54) ANTI-GAMMA DELTA TCR ANTIBODIES AND USES THEREOF