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(11)

EP 4 771 054 A1

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(43) Date of publication: 08.07.2026 Bulletin 2026/28 (21) Application number: 24858723.0 (22) Date of filing: 30.08.2024

(51) International Patent Classification (IPC):  C07K 16/28(2006.01) A61K 39/395(2006.01) C12N 15/63(2006.01) A61P 35/00(2006.01) (52) Cooperative Patent Classification (CPC): A61P 35/00; C07K 16/2827; C07K 2317/92; C07K 2317/76; C07K 2317/24; C07K 2317/73; C07K 2317/33; A61K 2039/505 (86) International application number: PCT/CN2024/115788 (87) International publication number: WO 2025/045192 (06.03.2025 Gazette 2025/10)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC ME MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA Designated Validation States: GE KH MA MD TN (30) Priority: 31.08.2023 US 202363535618 P (71) Applicant: Biosion Inc. Nanjing, Jiangsu 210061 (CN)	(72) Inventors: LI, Jun Nanjing, Jiangsu 210061 (CN) PENG, Zeyu Nanjing, Jiangsu 210061 (CN) CHEN, Mingjiu Nanjing, Jiangsu 210061 (CN) (74) Representative: Krauss, Jan  SKM-IP PartGmbB Oberanger 45 80331 München 80331 München (DE)