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(11)

EP 4 771 056 A1

(12)

(43) Date of publication: 08.07.2026 Bulletin 2026/28 (21) Application number: 24861147.7 (22) Date of filing: 30.08.2024

(51) International Patent Classification (IPC):  C07K 16/28(2006.01) A61P 35/00(2006.01) A61K 39/395(2006.01) (52) Cooperative Patent Classification (CPC): A61P 35/00; C07K 16/2803; C07K 2317/92; C07K 2317/76; C07K 2317/94; C07K 2317/73 (86) International application number: PCT/US2024/044683 (87) International publication number: WO 2025/049915 (06.03.2025 Gazette 2025/10)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC ME MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA Designated Validation States: GE KH MA MD TN (30) Priority: 31.08.2023 US 202363579866 P 11.12.2023 US 202363608778 P (71) Applicant: Exelixis, Inc. Alameda, CA 94502 (US)	(72) Inventors: BALIGA, Ramesh Alameda, CA 94502 (US) BATES, Amber, M. Alameda, CA 94502 (US) DAVIS, Jonathan, Harry Alameda, CA 94502 (US) HAMMER, Bonnie Alameda, CA 94502 (US) KANTAK, Seema Alameda, CA 94502 (US) LEE, John, Kyong-Won Alameda, CA 94502 (US) PULUKKUNAT, Dileep, K. Alameda, CA 94502 (US) (74) Representative: Jones Day  Gewürzmühlstr. 11 80538 München 80538 München (DE)