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(11)

EP 4 771 057 A1

(12)

(43) Date of publication: 08.07.2026 Bulletin 2026/28 (21) Application number: 24861242.6 (22) Date of filing: 30.08.2024

(51) International Patent Classification (IPC):  C07K 16/28(2006.01) C12N 5/0781(2010.01) C12N 15/79(2006.01) A01K 67/0278(2024.01) (52) Cooperative Patent Classification (CPC): A01K 67/0278; A01K 2227/105; A01K 2217/072; A01K 2267/01; C12N 15/8509; C12N 2015/8518; C40B 40/02; C12N 5/0635; C12N 2510/00; C07K 16/00; C07K 2317/92; C07K 16/18; C07K 2317/515; C07K 2317/565 (86) International application number: PCT/US2024/044892 (87) International publication number: WO 2025/050061 (06.03.2025 Gazette 2025/10)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC ME MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA Designated Validation States: GE KH MA MD TN (30) Priority: 31.08.2023 US 202363536002 P (71) Applicant: Xencor, Inc. Pasadena, CA 91107 (US)	(72) Inventors: KOENIG, Patrick Sunnyvale, California 94086 (US) LARRABEE, Lance Sunnyvale, California 94086 (US) RONG, Yinghui Sunnyvale, California 94086 (US) (74) Representative: Mewburn Ellis LLP  Aurora Building Counterslip Bristol BS1 6BX Bristol BS1 6BX (GB)