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EP 4 771 132 A1

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(43) Date of publication: 08.07.2026 Bulletin 2026/28 (21) Application number: 24776150.5 (22) Date of filing: 30.08.2024

(51) International Patent Classification (IPC):  C12N 7/00(2006.01) C12N 5/10(2006.01) A61P 35/00(2006.01) C07K 14/08(2006.01) A61K 35/768(2015.01) (52) Cooperative Patent Classification (CPC): C07K 14/005; C12N 2760/10022; C12N 7/00; C12N 2760/10032; C12N 2760/20232; C12N 2760/10051; A61P 35/00; A61K 38/00; A61K 35/76 (86) International application number: PCT/EP2024/074351 (87) International publication number: WO 2025/046106 (06.03.2025 Gazette 2025/10)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC ME MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA Designated Validation States: GE KH MA MD TN (30) Priority: 31.08.2023 EP 23194741 (71) Applicant: Abalos Therapeutics GmbH 40225 Düsseldorf (DE)

(72) Inventors: VOLLMER , Jörg 40225 Düsseldorf (DE) KOSTKA, Marcus 88400 Biberach an der Riß (DE) LANG, Karl Sebastian 45149 Essen (DE) LANG, Philipp 40001 Düsseldorf (DE) MACHLAH, Yara Maria 45147 Essen (DE) HARDT, Cornelia 44791 Bochum (DE) SCHMITZ, Rosa 82538 Geretsried (DE) SCHILLER, Maximilian 45131 Essen (DE) HOLNSTEINER, Lisa 40001 Düsseldorf (DE) ZÖLLER, Julia 40225 Düsseldorf (DE) WANG, Ruifeng 40001 Düsseldorf (DE) PANDEY, Piyush Sureshkumar 40001 Düsseldorf (DE) BERGERHAUSEN, Michael 40225 Düsseldorf (DE) FRIEDRICH-BECKER, Sarah-Kim 40225 Düsseldorf (DE) (74) Representative: Schiweck Weinzierl Koch Patentanwälte Partnerschaft mbB  Ganghoferstraße 68 B 80339 München 80339 München (DE)