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EP 4 771 137 A1

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(43) Date of publication: 08.07.2026 Bulletin 2026/28 (21) Application number: 24861062.8 (22) Date of filing: 29.08.2024

(51) International Patent Classification (IPC):  C12N 9/10(2006.01) C12N 9/22(2006.01) C07K 14/47(2006.01) (52) Cooperative Patent Classification (CPC): C12N 9/22; C12N 9/1007; C12Y 201/01037; C07K 2319/09; C07K 2319/80; C12N 2310/20; C07K 14/705; C12N 15/1138 (86) International application number: PCT/US2024/044497 (87) International publication number: WO 2025/049789 (06.03.2025 Gazette 2025/10)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC ME MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA Designated Validation States: GE KH MA MD TN (30) Priority: 01.09.2023 US 202363580330 P 09.11.2023 US 202363597676 P (71) Applicant: nChroma Bio, Inc. Boston, MA 02215 (US)	(72) Inventors: COLLINS, McKensie, Alexis Boston, MA 02215 (US) FRIEDLAND, Ari Boston, MA 02215 (US) JAFFE, Aron, Brandon Boston, MA 02215 (US) MYER, Vic Boston, MA 02215 (US) RAMIREZ, Ricardo, Noel Boston, MA 02215 (US) SCHAFER, Jamie, Lynn Boston, MA 02215 (US) (74) Representative: Hoffmann Eitle  Patent- und Rechtsanwälte PartmbB Arabellastraße 30 81925 München 81925 München (DE)