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(11)

EP 4 771 150 A1

(12)

(43) Date of publication: 08.07.2026 Bulletin 2026/28 (21) Application number: 24765107.8 (22) Date of filing: 29.08.2024

(51) International Patent Classification (IPC):  C12N 15/11(2006.01) C12N 15/67(2006.01) (52) Cooperative Patent Classification (CPC): C12N 15/111; C12N 2310/532; C12N 2310/12; C12N 15/64   C-Sets: C12N 15/64, C12Q 2521/337; (86) International application number: PCT/EP2024/074233 (87) International publication number: WO 2025/046039 (06.03.2025 Gazette 2025/10)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC ME MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA Designated Validation States: GE KH MA MD TN (30) Priority: 01.09.2023 GB 202313326 (71) Applicant: United Kingdom Research and Innovation Swindon SN2 1FL (GB)	(72) Inventors: DU, Yifei Cambridge CB2 0QH (GB) RAMAKRISHNAN, Venkatraman Cambridge CB2 0QH (GB) (74) Representative: Mewburn Ellis LLP  Aurora Building Counterslip Bristol BS1 6BX Bristol BS1 6BX (GB)