(19)

(11)

EP 4 771 160 A2

(12)

(88) Date of publication A3: 19.06.2025 (43) Date of publication: 08.07.2026 Bulletin 2026/28 (21) Application number: 24860883.8 (22) Date of filing: 27.08.2024

(51) International Patent Classification (IPC):  C12N 15/54(2006.01) C12N 15/90(2006.01) C12N 15/85(2006.01) (52) Cooperative Patent Classification (CPC): A61K 31/711; A61K 45/06 (86) International application number: PCT/US2024/044040 (87) International publication number: WO 2025/049480 (06.03.2025 Gazette 2025/10)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC ME MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA Designated Validation States: GE KH MA MD TN (30) Priority: 31.08.2023 US 202363536013 P (71) Applicant: Visgenx, Inc. Rancho Mission Viejo, CA 92694 (US)	(72) Inventors: CHAVEZ, Christopher Mission Viejo, California 92694 (US) EMANUELE, Martin Mission Viejo, California 92694 (US) (74) Representative: Zacco Sweden AB  P.O. Box 5581 Löjtnantsgatan 21 114 85 Stockholm 114 85 Stockholm (SE)