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EP 4 771 170 A2

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(88) Date of publication A3: 03.04.2025 (43) Date of publication: 08.07.2026 Bulletin 2026/28 (21) Application number: 24772834.8 (22) Date of filing: 29.08.2024

(51) International Patent Classification (IPC):  C12Q 1/6804(2018.01) (52) Cooperative Patent Classification (CPC): C12Q 1/6804   C-Sets: C12Q 1/6804, C12Q 2525/204, C12Q 2525/205, C12Q 2533/101, C12Q 2537/143, C12Q 2563/149, C12Q 2565/519; C12Q 1/6804, C12Q 2525/205, C12Q 2533/101, C12Q 2537/143; C12Q 1/6804, C12Q 2521/301, C12Q 2525/205, C12Q 2533/101, C12Q 2537/143; (86) International application number: PCT/US2024/044392 (87) International publication number: WO 2025/049720 (06.03.2025 Gazette 2025/10)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC ME MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA Designated Validation States: GE KH MA MD TN (30) Priority: 31.08.2023 US 202363535912 P (71) Applicant: Illumina, Inc. San Diego, CA 92122 (US)	(72) Inventors: SLATTER, Andrew Cambridge Cambridgeshire CB21 6DF (GB) CAO, Yang Cambridge Cambridgeshire CB21 6DF (GB) ALEMAN GARCIA, Miguel Angel Cambridge Cambridgeshire CB21 6DF (GB) (74) Representative: Williams, Andrea  Marks & Clerk LLP 62-68 Hills Road Cambridge CB2 1LA Cambridge CB2 1LA (GB)