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EP 4 771 178 A1

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(43) Date of publication: 08.07.2026 Bulletin 2026/28 (21) Application number: 24773653.1 (22) Date of filing: 03.09.2024

(51) International Patent Classification (IPC):  C12Q 1/6844(2018.01) C12Q 1/70(2006.01) C12Q 1/6827(2018.01) (52) Cooperative Patent Classification (CPC): C12Q 1/6844; C12Q 1/701; C12Q 1/6827   C-Sets: C12Q 1/6844, C12Q 2531/101; C12Q 1/6827, C12Q 2531/101; (86) International application number: PCT/US2024/045060 (87) International publication number: WO 2025/050131 (06.03.2025 Gazette 2025/10)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC ME MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA Designated Validation States: GE KH MA MD TN (30) Priority: 01.09.2023 US 202363580287 P (71) Applicant: ABBOTT LABORATORIES Abbott Park, IL 60064-6008 (US)

(72) Inventors: MORRIS, Andrew Abbott Park, IL 60064 (US) KORANDA, Jessica Abbott Park, IL 60064 (US) ZHANG, Yangrong Abbott Park, IL 60064 (US) TANAKA, Kari Abbott Park, IL 60064 (US) NETO, Mario Abbott Park, IL 60064 (US) ABBOTT, Jamie Abbott Park, IL 60064 (US) TORONEY, Rebecca Abbott Park, IL 60064 (US) COLLINS, Caitlin Abbott Park, IL 60064 (US) TEOH, Wei Ping Abbott Park, IL 60064 (US) FRANKEL, Matthew Abbott Park, IL 60064 (US) SACHDEV, Divya Abbott Park, IL 60064 (US) (74) Representative: Carpmaels & Ransford LLP  One Southampton Row London WC1B 5HA London WC1B 5HA (GB)