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EP 4 777 087 A1

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(43) Date of publication: 22.07.2026 Bulletin 2026/30 (21) Application number: 24863884.3 (22) Date of filing: 13.09.2024

(51) International Patent Classification (IPC):  A61K 9/51(2006.01) A61K 31/05(2006.01) A61K 33/24(2019.01) A61K 33/34(2006.01) A61K 9/00(2006.01) A61K 31/25(2006.01) A61K 33/26(2006.01) C12N 15/87(2006.01) (52) Cooperative Patent Classification (CPC): C12N 15/87; A61K 48/0025; A61K 48/0041; C12N 15/90; A61K 48/005; A61K 31/7105 (86) International application number: PCT/AU2024/050983 (87) International publication number: WO 2025/054668 (20.03.2025 Gazette 2025/12)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC ME MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA Designated Validation States: GE KH MA MD TN (30) Priority: 14.09.2023 AU 2023902964 (71) Applicant: The University of Melbourne Victoria 3010 (AU)	(72) Inventors: CARUSO, Francesco Melbourne, Victoria 3010 (AU) CHEN, Jingqu Melbourne, Victoria 3010 (AU) CORTEZ-JUGO, Christina Melbourne, Victoria 3010 (AU) GU, Yuang Melbourne, Victoria 3010 (AU) (74) Representative: Murgitroyd & Company  165-169 Scotland Street Glasgow G5 8PL Glasgow G5 8PL (GB)