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(11)

EP 4 798 069 A1

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(43) Date of publication: 02.09.2026 Bulletin 2026/36 (21) Application number: 24883273.5 (22) Date of filing: 23.10.2024

(51) International Patent Classification (IPC):  A61B 5/31(2021.01) A61B 5/16(2006.01) A61N 1/05(2006.01) A61B 5/291(2021.01) A61B 5/369(2021.01) A61N 1/08(2006.01) (52) Cooperative Patent Classification (CPC): A61B 5/165; A61B 5/37; A61B 5/374; A61B 5/4836; A61N 1/0534; A61N 1/36096; A61N 1/36139 (86) International application number: PCT/US2024/052647 (87) International publication number: WO 2025/090661 (01.05.2025 Gazette 2025/18)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC ME MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA Designated Validation States: GE KH MA MD TN (30) Priority: 23.10.2023 US 202363592453 P (71) Applicants: Baylor College of Medicine Houston, TX 77030 (US) Washington University St. Louis, Missouri 63130 (US)	(72) Inventors: BIJANKI, Kelly Houston, Texas 77030 (US) HACKER, Carl St. Louis, Missouri 63130 (US) MOCCHI, Madaline Houston, Texas 77030 (US) (74) Representative: Grünecker Patent- und Rechtsanwälte PartG mbB  Leopoldstraße 4 80802 München 80802 München (DE)