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EP 4 798 174 A1

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(43) Date of publication: 02.09.2026 Bulletin 2026/36 (21) Application number: 24883142.2 (22) Date of filing: 21.10.2024

(51) International Patent Classification (IPC):  A61K 9/20(2006.01) A61K 47/12(2006.01) C07C 51/43(2006.01) C07C 51/41(2006.01) C11C 3/00(2006.01) (52) Cooperative Patent Classification (CPC): A61K 9/14; A61K 9/2013; A61K 9/2054; A61K 9/2018; C07C 53/126; C07C 51/412   C-Sets: C07C 51/412, C07C 53/126; (86) International application number: PCT/US2024/052178 (87) International publication number: WO 2025/090400 (01.05.2025 Gazette 2025/18)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC ME MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA Designated Validation States: GE KH MA MD TN (30) Priority: 25.10.2023 US 202363593167 P 11.10.2024 US 202463706065 P (71) Applicant: Merck Sharp & Dohme LLC Rahway, New Jersey 07065 (US)

(72) Inventors: TERIFE, Graciela Rahway, New Jersey 07065 (US) ESCOTET ESPINOZA, Manuel Sebastian Rahway, New Jersey 07065 (US) PARKER, Andrew Stevens Rahway, New Jersey 07065 (US) KLINZING, Gerard R. Rahway, New Jersey 07065 (US) KORANNE, Sampada Rahway, New Jersey 07065 (US) BOOKWALA, Mustafa Rahway, New Jersey 07065 (US) (74) Representative: Merck Sharp & Dohme LLC  120 Moorgate London EC2M 6UR London EC2M 6UR (GB)