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EP 4 798 189 A1

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(43) Date of publication: 02.09.2026 Bulletin 2026/36 (21) Application number: 24883434.3 (22) Date of filing: 25.10.2024

(51) International Patent Classification (IPC):  A61K 31/395(2006.01) A61K 31/167(2006.01) A61K 31/33(2006.01) A61K 31/445(2006.01) A61K 31/4245(2006.01) (52) Cooperative Patent Classification (CPC): A61P 25/28; C07D 413/06; C07D 413/14; A61K 31/454 (86) International application number: PCT/US2024/053056 (87) International publication number: WO 2025/090928 (01.05.2025 Gazette 2025/18)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC ME MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA Designated Validation States: GE KH MA MD TN (30) Priority: 25.10.2023 US 202363545709 P 26.07.2024 US 202463676131 P (71) Applicant: Aquinnah Pharmaceuticals, Inc. Cambridge, MA 02139 (US)	(72) Inventor: VACCA, Joseph P. Cambridge, Massachusetts 02139 (US) (74) Representative: Harris, Jennifer Lucy et al Kilburn & Strode LLP Lacon London 84 Theobalds Road London WC1X 8NL London WC1X 8NL (GB)