(19)
(11) EP 4 798 196 A1

(12)

(43) Date of publication:
02.09.2026 Bulletin 2026/36

(21) Application number: 24794804.5

(22) Date of filing: 25.10.2024
(51) International Patent Classification (IPC): 
A61K 31/4365(2006.01)
A61K 31/5375(2006.01)
 A61K 31/519(2006.01)
A61P 35/00(2006.01)
(52) Cooperative Patent Classification (CPC):
A61K 31/519; A61K 31/5375; A61K 31/4365; A61P 35/00
(86) International application number:
PCT/EP2024/080170
(87) International publication number:
WO 2025/088087 (01.05.2025 Gazette 2025/18)
(84) Designated Contracting States:
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC ME MK MT NL NO PL PT RO RS SE SI SK SM TR
Designated Extension States:
BA
Designated Validation States:
GE KH MA MD TN

(30) Priority: 25.10.2023 EP 23205931
31.10.2023 EP 23207212
28.06.2024 EP 24185254
28.06.2024 EP 24185263

(71) Applicant: Eisbach Bio GmbH
82152 Martinsried (DE)

(72) Inventors:
  • MENZER, William
    82152 Planegg (DE)
  • LECHNER, Markus
    Munich 80638 (DE)
  • SCHOMBURG, Adrian
    82166 Gräfelfing (DE)

(74) Representative: Zwicker, Jörk 
Zwicker Schnappauf & Partner Patentanwälte PartG mbB Hansastraße 32
80686 München
80686 München (DE)

   


(54) A PYRIDO-THIENO-PYRIMIDIN DERIVATIVE AS ALC1 INHIBITOR FOR USE IN THE TREATMENT OF HOMOLOGOUS RECOMBINATION DEFICIENCY (HRD) CANCERS