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EP 4 798 230 A2

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(88) Date of publication A3: 19.06.2025 (43) Date of publication: 02.09.2026 Bulletin 2026/36 (21) Application number: 24827126.4 (22) Date of filing: 25.10.2024

(51) International Patent Classification (IPC):  A61K 39/00(2006.01) C12N 15/86(2006.01) A61K 48/00(2006.01) (52) Cooperative Patent Classification (CPC): C12N 15/86; C12N 2710/10343; C12N 2710/10322; C12N 2810/6018; A61K 39/12; A61P 31/20; A61P 35/00; A61K 2039/572; A61K 35/761; A61K 2039/585; A61K 2039/5256   C-Sets: A61K 35/761, A61K 2300/00; (86) International application number: PCT/IB2024/000596 (87) International publication number: WO 2025/088378 (01.05.2025 Gazette 2025/18)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC ME MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA Designated Validation States: GE KH MA MD TN (30) Priority: 25.10.2023 US 202363593110 P (71) Applicant: Infinitopes Limited Oxford Oxfordshire OX3 7FZ (GB)

(72) Inventors: CHINNAKANNAN, Senthil Oxford Oxfordshire OX3 7FZ (GB) KWOK, Jonathan Oxford Oxfordshire OX3 7FZ (GB) LEE, Lian, Ni Oxford Oxfordshire OX3 7FZ (GB) BOKUM, Annemieke, Ten Oxford Oxfordshire OX3 7FZ (GB) MARINOU, Spyridoula Oxford Oxfordshire OX3 7FZ (GB) TONG, Orion Oxford Oxfordshire OX3 7FZ (GB) (74) Representative: Brand Murray Fuller LLP  111 Wardour Street London W1F 0UH London W1F 0UH (GB)