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EP 4 798 231 A1

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(43) Date of publication: 02.09.2026 Bulletin 2026/36 (21) Application number: 24883386.5 (22) Date of filing: 25.10.2024

(51) International Patent Classification (IPC):  A61K 39/00(2006.01) A61K 38/17(2006.01) C12N 15/85(2006.01) C07K 14/705(2006.01) C07K 7/06(2006.01) A61P 35/00(2006.01) (52) Cooperative Patent Classification (CPC): A61P 35/00; A61K 40/11; C07K 14/4748; G01N 33/56977; G01N 33/505; G01N 2800/52; A61K 40/32; A61K 40/4268; A61K 39/0011; A61K 2039/572; G01N 33/57557 (86) International application number: PCT/US2024/052934 (87) International publication number: WO 2025/090850 (01.05.2025 Gazette 2025/18)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC ME MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA Designated Validation States: GE KH MA MD TN (30) Priority: 27.10.2023 US 202363546105 P 16.02.2024 US 202463554734 P (71) Applicant: Tscan Therapeutics, Inc. Waltham, MA 02451 (US)	(72) Inventors: NABILSI, Nancy Waltham, MA 02451 (US) TADROS, Jenny Waltham, MA 02451 (US) JUREWICZ, Mollie, M. Waltham, MA 02451 (US) MACBEATH, Gavin Waltham, MA 02451 (US) (74) Representative: Leonard, Thomas Charles et al Kilburn & Strode LLP Lacon London 84 Theobalds Road London WC1X 8NL London WC1X 8NL (GB)