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EP 4 798 235 A2

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(88) Date of publication A3: 12.06.2025 (43) Date of publication: 02.09.2026 Bulletin 2026/36 (21) Application number: 24883323.8 (22) Date of filing: 24.10.2024

(51) International Patent Classification (IPC):  A61K 39/39(2006.01) A61P 37/04(2006.01) A61K 39/00(2006.01) A61P 35/00(2006.01) A61K 9/00(2006.01) (52) Cooperative Patent Classification (CPC): A61K 38/208; A61K 38/193; A61K 9/0024; A61K 9/501   C-Sets: A61K 38/208, A61K 2300/00; A61K 38/193, A61K 2300/00; (86) International application number: PCT/US2024/052802 (87) International publication number: WO 2025/090756 (01.05.2025 Gazette 2025/18)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC ME MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA Designated Validation States: GE KH MA MD TN (30) Priority: 24.10.2023 US 202363545547 P (71) Applicant: Attivare Therapeutics Inc. Natick, MA 01760 (US)

(72) Inventors: PIERCE, Robert Natick, Massachusetts 01760 (US) MCDONOUGH, Jessica Natick, Massachusetts 01760 (US) LANGELLOTTO, Fernanda Natick, Massachusetts 01760 (US) MANDLEY, Everton Natick, Massachusetts 01760 (US) DOHERTY, Edward Natick, Massachusetts 01760 (US) (74) Representative: Grund, Martin et al Grund Intellectual Property Group Patentanwälte und Solicitor PartG mbB Steinsdorfstraße 2 80538 München 80538 München (DE)