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EP 4 798 240 A1

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(43) Date of publication: 02.09.2026 Bulletin 2026/36 (21) Application number: 24799649.9 (22) Date of filing: 22.10.2024

(51) International Patent Classification (IPC):  A61K 40/11(2025.01) A61K 40/42(2025.01) A61K 40/31(2025.01) A61P 37/00(2006.01) (52) Cooperative Patent Classification (CPC): A61K 40/4211; A61K 40/31; A61K 40/11; A61P 37/00; C07K 2317/622; A61K 2239/31; A61K 40/416; A61K 2239/38 (86) International application number: PCT/GB2024/052698 (87) International publication number: WO 2025/088308 (01.05.2025 Gazette 2025/18)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC ME MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA Designated Validation States: GE KH MA MD TN (30) Priority: 23.10.2023 GB 202316183 27.03.2024 GB 202404412 29.08.2024 GB 202412689 26.09.2024 GB 202414148 (71) Applicant: Autolus Limited London W12 7FP (GB)	(72) Inventors: BRUGGER, Wolfram London W12 7FP (GB) PITTARI, Gianfranco London W12 7FP (GB) DAVIES, Michelle London W12 7FP (GB) ROSSATO, Gianluca London W12 7FP (GB) ZHANG, Yiyun London W12 7FP (GB) PULÉ, Martin London W12 7FP (GB) WHITROW, Helen London W12 7FP (GB) (74) Representative: D Young & Co LLP  3 Noble Street London EC2V 7BQ London EC2V 7BQ (GB)