(19)

(11)

EP 4 798 244 A1

(12)

(43) Date of publication: 02.09.2026 Bulletin 2026/36 (21) Application number: 24883351.9 (22) Date of filing: 24.10.2024

(51) International Patent Classification (IPC):  A61K 47/54(2017.01) A61K 31/352(2006.01) A61P 13/12(2006.01) (52) Cooperative Patent Classification (CPC): A61P 13/12; A61K 47/549 (86) International application number: PCT/US2024/052857 (87) International publication number: WO 2025/090796 (01.05.2025 Gazette 2025/18)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC ME MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA Designated Validation States: GE KH MA MD TN (30) Priority: 24.10.2023 US 202363592867 P (71) Applicant: University of Connecticut Farmington, CT 06032 (US)	(72) Inventors: BAHAL, Raman Glastonbury, Connecticut 06033 (US) WAHANE, Aniket Manchester, Connecticut 06042 (US) KUMAR, Vikas Willimantic, Connecticut 06226 (US) (74) Representative: Casci, Tamara et al Barzanò & Zanardo S.p.A. Via Borgonuovo, 10 20121 Milano 20121 Milano (IT)