(19)
(11) EP 4 798 261 A1

(12)

(43) Date of publication:
02.09.2026 Bulletin 2026/36

(21) Application number: 24883493.9

(22) Date of filing: 28.10.2024
(51) International Patent Classification (IPC): 
A61L 27/20(2006.01)
B33Y 10/00(2015.01)
A61K 35/12(2015.01)
A61L 27/18(2006.01)
A61K 47/32(2006.01)
 A61P 7/00(2006.01)
C12N 5/10(2006.01)
A61K 47/36(2006.01)
A61K 38/00(2006.01)
(52) Cooperative Patent Classification (CPC):
A61K 38/00; A61L 27/20; A61P 7/00; B33Y 80/00; A61L 27/52; A61L 27/507; A61L 27/54; A61L 2430/00; A61L 27/38; A61L 27/3804; A61L 2300/41; A61L 27/222; B33Y 70/00; C12N 2533/74; C12N 5/069; C12N 2513/00; A61K 35/44; A61K 35/36; A61K 9/06; A61K 47/42
 
C-Sets:
A61L 27/20, C08L 5/04;
(86) International application number:
PCT/US2024/053212
(87) International publication number:
WO 2025/091008 (01.05.2025 Gazette 2025/18)
(84) Designated Contracting States:
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC ME MK MT NL NO PL PT RO RS SE SI SK SM TR
Designated Extension States:
BA
Designated Validation States:
GE KH MA MD TN

(30) Priority: 27.10.2023 US 202363593840 P
17.04.2024 US 202463635145 P
08.07.2024 US 202463668540 P

(71) Applicants:
  • William Marsh Rice University
    Houston, TX 70112 (US)
  • Board of Regents, The University of Texas System
    Austin, TX 78701 (US)

(72) Inventors:
  • VEISEH, Omid
    Houston, Texas 77005 (US)
  • FOWLER, Martha
    Houston, Texas 77005 (US)
  • PANDEY, Shalini
    Houston, Texas 77005 (US)
  • LOZANO, Alvaro Moreno
    Houston, Texas 77005 (US)
  • KRAUSE, Julian
    Houston, Texas 77005 (US)
  • ZHANG, Qixu
    Houston, Texas 77030 (US)
  • WU, Yewen
    Houston, Texas 77030 (US)

(74) Representative: HGF 
HGF Limited 4th Floor, 1 City Square
Leeds LS1 2ES
Leeds LS1 2ES (GB)

   


(54) THREE-DIMENSIONAL ENGINEERED LYMPHATIC AND ASSOCIATED TISSUE GRAFTS