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(11)

EP 4 798 589 A1

(12)

(43) Date of publication: 02.09.2026 Bulletin 2026/36 (21) Application number: 24883360.0 (22) Date of filing: 24.10.2024

(51) International Patent Classification (IPC):  C07D 471/22(2006.01) C07D 498/18(2006.01) C07D 513/18(2006.01) A61K 31/504(2006.01) A61P 35/00(2006.01) C07D 498/22(2006.01) C07D 513/22(2006.01) C07D 498/08(2006.01) A61K 31/519(2006.01) (52) Cooperative Patent Classification (CPC): A61P 35/00; C07D 471/22; C07D 498/08; C07D 498/18; C07D 498/22; C07D 513/18; C07D 513/22; A61K 45/06 (86) International application number: PCT/US2024/052875 (87) International publication number: WO 2025/090809 (01.05.2025 Gazette 2025/18)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC ME MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA Designated Validation States: GE KH MA MD TN (30) Priority: 25.10.2023 US 202363593007 P (71) Applicant: Kumquat Biosciences Inc. San Diego, CA 92121 (US)	(72) Inventors: WU, Baogen San Diego, California 92121 (US) CHEN, Zhiyong San Diego, California 92121 (US) REN, Pingda San Diego, California 92121 (US) (74) Representative: J A Kemp LLP  80 Turnmill Street London EC1M 5QU London EC1M 5QU (GB)