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(11)

EP 4 798 592 A1

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(43) Date of publication: 02.09.2026 Bulletin 2026/36 (21) Application number: 24804671.6 (22) Date of filing: 24.10.2024

(51) International Patent Classification (IPC):  C07D 498/04(2006.01) A61P 17/06(2006.01) A61P 37/00(2006.01) C07D 519/00(2006.01) A61P 29/00(2006.01) A61K 31/553(2006.01) (52) Cooperative Patent Classification (CPC): C07D 519/00; C07D 498/04; A61P 17/06; A61P 29/00; A61P 37/00 (86) International application number: PCT/US2024/052804 (87) International publication number: WO 2025/090758 (01.05.2025 Gazette 2025/18)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC ME MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA Designated Validation States: GE KH MA MD TN (30) Priority: 27.10.2023 US 202363593599 P 26.04.2024 US 202463639359 P (71) Applicant: Eli Lilly and Company Indianapolis, IN 46285 (US)

(72) Inventors: CARSON, Cheryl Ann Indianapolis, Indiana 46206-6288 (US) CLARKE, Christian Alexander Indianapolis, Indiana 46206-6288 (US) DORSEY, Frank Charles Indianapolis, Indiana 46206-6288 (US) GERNERT, Douglas L. Indianapolis, Indiana 46206-6288 (US) HOLLOWAY, William Glen Indianapolis, Indiana 46206-6288 (US) MCMILLEN, William Thomas Indianapolis, Indiana 46206-6288 (US) NIKOLAOU, Christodoulos Indianapolis, Indiana 46206-6288 (US) (74) Representative: J A Kemp LLP  80 Turnmill Street London EC1M 5QU London EC1M 5QU (GB)