(19)
(11) EP 4 798 608 A1

(12)

(43) Date of publication:
02.09.2026 Bulletin 2026/36

(21) Application number: 24883284.2

(22) Date of filing: 23.10.2024
(51) International Patent Classification (IPC): 
C07K 14/00(2006.01)
C12N 15/85(2006.01)
A61K 38/00(2006.01)
(52) Cooperative Patent Classification (CPC):
A61K 38/00; C12N 15/85; C12N 15/88; C07K 2319/04
(86) International application number:
PCT/US2024/052669
(87) International publication number:
WO 2025/090678 (01.05.2025 Gazette 2025/18)
(84) Designated Contracting States:
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC ME MK MT NL NO PL PT RO RS SE SI SK SM TR
Designated Extension States:
BA
Designated Validation States:
GE KH MA MD TN

(30) Priority: 23.10.2023 US 202363592492 P
01.12.2023 US 202363605418 P

(71) Applicant: The Board of Regents of the University of Texas System
Austin, Texas 78701 (US)

(72) Inventors:
  • SIEGWART, Daniel J.
    Dallas, Texas 75390 (US)
  • FARBIAK, Lukas
    Dallas, Texas 75390 (US)
  • MILLER, William
    Dallas, Texas 5390 (US)

(74) Representative: Potter Clarkson 
Chapel Quarter Mount Street
Nottingham NG1 6HQ
Nottingham NG1 6HQ (GB)

   


(54) NOVEL ENDOPLASMIC RETICULUM TARGETING SIGNAL PEPTIDES AND USES THEREOF