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(11)

EP 4 798 629 A1

(12)

(43) Date of publication: 02.09.2026 Bulletin 2026/36 (21) Application number: 24881894.0 (22) Date of filing: 26.10.2024

(51) International Patent Classification (IPC):  C07K 16/30(2006.01) A61P 35/00(2006.01) C12N 15/85(2006.01) A61K 39/395(2006.01) C12N 15/62(2006.01) (52) Cooperative Patent Classification (CPC): A61P 35/00; C07K 2319/00; C07K 2317/31; C07K 2317/622; C07K 2317/624; C07K 2317/94; C07K 16/2809; C07K 16/2878; C07K 2317/53; C07K 2317/526; C07K 2317/55; C07K 2317/567; C07K 2317/92 (86) International application number: PCT/IB2024/060551 (87) International publication number: WO 2025/088587 (01.05.2025 Gazette 2025/18)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC ME MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA Designated Validation States: GE KH MA MD TN (30) Priority: 27.10.2023 US 202363593652 P 30.08.2024 US 202463689053 P (71) Applicant: Janssen Biotech, Inc. Horsham, PA 19044 (US)

(72) Inventors: LUO, Jinquan Spring House, Pennsylvania 19477 (US) DIEM, Michael Spring House, Pennsylvania 19477 (US) HUANG, Chichi Malvern, Pennsylvania 19355 (US) TEPLYAKOV, Alexey Spring House, Pennsylvania 19477 (US) BOUCHER, Lauren Raritan, New Jersey 08869 (US) FELDKAMP, Michael Spring House, Pennsylvania 19477 (US) ARMSTRONG, Anthony Spring House, Pennsylvania 19477 (US) PRINSLOW, Elisabeth G. Spring House, Pennsylvania 19477 (US) (74) Representative: Carpmaels & Ransford LLP  One Southampton Row London WC1B 5HA London WC1B 5HA (GB)