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EP 4 798 699 A1

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(43) Date of publication: 02.09.2026 Bulletin 2026/36 (21) Application number: 24800898.9 (22) Date of filing: 22.10.2024

(51) International Patent Classification (IPC):  C12N 5/0783(2010.01) A61K 40/00(2025.01) A61K 40/31(2025.01) C07K 14/725(2006.01) A61K 35/17(2025.01) A61K 40/11(2025.01) A61K 40/42(2025.01) C12N 15/867(2006.01) (52) Cooperative Patent Classification (CPC): C12N 5/0636; C12N 2510/00; C07K 14/7051; A61K 40/11; A61K 40/4211; A61K 40/31; C12N 2501/515; C12N 2501/51; C12N 2740/16043; C12N 2740/13043 (86) International application number: PCT/GB2024/052697 (87) International publication number: WO 2025/088307 (01.05.2025 Gazette 2025/18)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC ME MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA Designated Validation States: GE KH MA MD TN (30) Priority: 23.10.2023 GB 202316184 (71) Applicant: Autolus Limited London W12 7FP (GB)	(72) Inventors: LILOVA, Kostadinka London W12 7FP (GB) SANTIAGO TOLEDO, Gerardo London W12 7FP (GB) WILLIAMS, Alexander London W12 7FP (GB) CULSHAW, Abigail London W12 7FP (GB) TAHEEM, Dheraj London W12 7FP (GB) (74) Representative: D Young & Co LLP  3 Noble Street London EC2V 7BQ London EC2V 7BQ (GB)