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(11)

EP 4 798 702 A1

(12)

(43) Date of publication: 02.09.2026 Bulletin 2026/36 (21) Application number: 24805004.9 (22) Date of filing: 23.10.2024

(51) International Patent Classification (IPC):  C12N 9/00(2006.01) C12N 9/10(2006.01) A61K 38/00(2006.01) C07K 14/47(2006.01) C12N 9/78(2006.01) (52) Cooperative Patent Classification (CPC): A61K 38/00; C12N 9/93; G01N 2333/9015; C12Y 305/04004; C12Y 603/02019; C07K 14/4702; C12N 9/10; C12N 9/78; C07K 14/4747; C07K 14/4738; C07K 14/47 (86) International application number: PCT/US2024/052569 (87) International publication number: WO 2025/090610 (01.05.2025 Gazette 2025/18)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC ME MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA Designated Validation States: GE KH MA MD TN (30) Priority: 26.10.2023 US 202363545875 P (71) Applicant: TRIANA Biomedicines, Inc. Lexington, MA 02421 (US)

(72) Inventors: BART, Aaron Lexington, MA 02421 (US) KAMADURAI, Hari Lexington, MA 02421 (US) MARCOUX, David Lexington, MA 02421 (US) LA, Daniel Lexington, MA 02421 (US) CONERY, Andrew, Ryan Belmont, MA 02478 (US) MEDIKONDA, Aravind, Prasad Lexington, MA 02421 (US) TROJER, Patrick Waltham, MA 02451 (US) SEYB, Kathleen Waltham, MA 02451 (US) WIGLE, Timothy Waltham, MA 02451 (US) (74) Representative: Potter Clarkson  Chapel Quarter Mount Street Nottingham NG1 6HQ Nottingham NG1 6HQ (GB)