(19)
(11) EP 4 798 703 A1

(12)

(43) Date of publication:
02.09.2026 Bulletin 2026/36

(21) Application number: 24883424.4

(22) Date of filing: 25.10.2024
(51) International Patent Classification (IPC): 
C12N 9/00(2006.01)
C12P 7/6409(2022.01)
C12N 15/70(2006.01)
C12N 15/52(2006.01)
(52) Cooperative Patent Classification (CPC):
C12N 15/70; C12P 7/6409; C12N 15/52; C12N 9/0008; C12Y 102/0103
(86) International application number:
PCT/US2024/053031
(87) International publication number:
WO 2025/090914 (01.05.2025 Gazette 2025/18)
(84) Designated Contracting States:
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC ME MK MT NL NO PL PT RO RS SE SI SK SM TR
Designated Extension States:
BA
Designated Validation States:
GE KH MA MD TN

(30) Priority: 27.10.2023 US 202363593879 P

(71) Applicant: Genomatica, Inc.
San Diego, CA 92121 (US)

(72) Inventors:
  • DE JESUS-KIM, Lorraine
    Boston, MA 02210 (US)
  • MARTINEZ DEL CAMPO, Ana, Elisa
    Boston, MA 02210 (US)
  • RITTER, Seth, C.
    Boston, MA 02210 (US)
  • RIVERA, Izarys
    Boston, MA 02210 (US)
  • SCHIRMER, Andreas, Walter
    San Diego, CA 92131 (US)

(74) Representative: Simmons & Simmons LLP (Munich) 
Lehel Carré Gewürzmühlstraße 11
80538 Munich
80538 Munich (DE)

   


(54) CARBOXYLIC ACID REDUCTASE VARIANTS AND METHODS OF USE