(19)
(11) EP 4 798 705 A1

(12)

(43) Date of publication:
02.09.2026 Bulletin 2026/36

(21) Application number: 24794160.2

(22) Date of filing: 24.10.2024
(51) International Patent Classification (IPC): 
C12N 9/12(2006.01)
 C12P 19/34(2006.01)
(52) Cooperative Patent Classification (CPC):
C12Y 207/07031; C12N 9/1264; C12P 19/34
(86) International application number:
PCT/EP2024/080046
(87) International publication number:
WO 2025/088024 (01.05.2025 Gazette 2025/18)
(84) Designated Contracting States:
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC ME MK MT NL NO PL PT RO RS SE SI SK SM TR
Designated Extension States:
BA
Designated Validation States:
GE KH MA MD TN

(30) Priority: 24.10.2023 EP 23306858

(71) Applicant: DNA Script
94270 Le Kremlin-Bicêtre (FR)

(72) Inventors:
  • SOSKINE, Mikhael
    94270 Le Kremlin-Bicêtre (FR)
  • JAZIRI, Faten
    94270 Le Kremlin-Bicêtre (FR)
  • MELLARE, Morgane
    94270 Le Kremlin-Bicêtre (FR)
  • DEGROTTE, Florent
    94270 Le Kremlin-Bicêtre (FR)
  • MOLINA, Manon
    94270 Le Kremlin-Bicêtre (FR)
  • MENDES, Clara
    94270 Le Kremlin-Bicêtre (FR)
  • LE COZ, Yann
    94270 Le Kremlin-Bicêtre (FR)

(74) Representative: Plasseraud IP 
104 Rue de Richelieu CS92104
75080 Paris Cedex 02
75080 Paris Cedex 02 (FR)

   


(54) NOVEL TERMINAL DEOXYNUCLEOTIDYL TRANSFERASE (TDT) VARIANTS AND USES THEREOF